Acromegaly and pregnancy: a prospective study

Acromegaly and pregnancy.

La GH placentaria (GH-V) se convierte en el componente principal de la GH circulante a partir del segundo trimestre de embarazo. La GH-V es secretada continuamente e induce la producción hepática materna de IGF-I que, en mujeres sanas, inhibe la secreción de GH hipofisaria. En mujeres acromegálicas embarazadas las células adenomatosas somatotropas son resistentes a la retroalimentación inhibido...

Pregnancy in acromegaly: a one-center experience.

OBJECTIVE AND DESIGN The aim of the study was the retrospective evaluation of pregnancy in acromegalic women attending our center. PATIENTS AND METHODS Six active acromegalic women (30-35-years old, disease duration 5-17 years) underwent seven pregnancies. Four patients had macroadenoma and two microadenoma; four had surgery; and two had been treated primarily with drugs. Before conception, G...

Anti-Coagulation During Pregnancy in Women with Mechanical Heart Valves: A Prospective Study

Effect of Depression, Stress and Anxiety during Pregnancy on Low Birth Weight: A Prospective Cohort Study in Suburban Communities

Background and Objectives: Pre-natal mental health problems are major causes of disease burden, especially in lower socio-economic groups of population. The present study used data of a prospective cohort study to estimate the risk of mental health problems, including depression, anxiety, and stress, on birth weight.   Materials and Methods: This study used data of 398 pregnant women who were...

pregnancy outcome after mechanical mitral valve replacement: a prospective study

background: pregnant patients with mechanical heart valves require anticoagulation. the risk of bleeding and embryopathy associated with oral anticoagulants must be weighed against the risk of valve thrombosis. methods: in this prospective study, undertaken between 1999 and 2009, 53 pregnancies (47 women with mechanical mitral valves; 29.8 ± 4.8 years old) were studied. patients were divided in...